Intranasal Delivery Benefits

img_1361Systemic intranasal drug delivery is expanding as a preferred route of administration because it avoids the issue of drug degradation in the gastrointestinal tract, provides a faster onset of action, is a painless alternative to injections, obviates the need for biohazardous disposal of needle sharps and can be self or caregiver administered.

Nose-To-Brain delivery is emerging as a non-invasive means of bypassing the Blood Brain Barrier to administer therapeutics for the treatment of neurodegenerative disorders such as Alzheimers, Parkinsons, Huntington, Traumatic Brain Injury and Glioblastoma. Mystic’s platform approach provides the option to optimize its Nose-To-Brain dispensers for neuroprotective and neurodegenerative therapeutics in liquid or powder forms.

Nasal delivery applications include therapeutics for neuroprotection, neuroregeneration, pain management, migraine crisis, hormone replacement, seizures, emesis, anxiety & depression, hypoglycemia & diabetes, growth deficiency, proteins & peptides, vaccines, immunomodulators and biomedical countermeasures. Our delivery system solutions offer a number of patient benefits and advantages to pharmaceutical manufacturers.

Benefits For Pharmaceutical Manufacturers:

  • Sterile products by aseptic process or terminal sterilization
  • Mono-dose, bi-dose or multi-dose with a variety of dispenser device configurations (disposable, reloadable)
  • Packaging design provides unmatched production flexbility and cost efficient storage/ transport options for Work In Process (“WIP”) or finished product
  • Calibrated, consistent and precise dose delivery with user independent actuation
  • Dispenser device actuation force can be calibrated to the needs of the patient population
  • Tamper resistant packaging
  • Superior barrier properties for shelf stability
  • Liquid, powder and reconstituted powder configuration options
  • Rapid Fill, Fit, Finish production capacity
  • Highly scalable aseptic fill fit finish capacities

Benefits For Patients:

  • Abuse resistant design
  • Side actuation dispense design to facilitate patient ease of use
  • Designed for self or caregiver based administration
  • No device priming required
  • Actuation force can be calibrated
  • Compact and easy to carry